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MYP_029906
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Basic Information
SrnA4
Antimicrobial
Standard
32 amino acids
C160H234N48O45S3
Standard
Sequence
GWSTAVRLTVQGRCGWWFTHSYECTSPNVRCG
Physicochemical Analysis
3646.06 Da
8.71
1.82
1.52
0.0569
-0.35
0.45
0.02
52.69
42.50
0.1562
17990.00
18115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1503.70
-17.09
59.0
51.0
109.0
256.0
10.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259778 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
N. gonorrhoeae V3091967
64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0302698 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S-mutans UA159
>64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0304442 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. pneumoniae V4122578 or W81002644
0.5-1 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0335794 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. pyogenes W51503011 or W80908630
16 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0353992 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
drug-resistant Enterococcus faecalis W82000259 or W80909324 or ATCC 29212
16-32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
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