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MYP_029906
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Basic Information
SrnA4
Antimicrobial
Standard
32 amino acids
C160H234N48O45S3
Standard
Sequence
GWSTAVRLTVQGRCGWWFTHSYECTSPNVRCG
Physicochemical Analysis
3646.06 Da
8.71
1.82
1.52
0.0569
-0.35
0.45
0.02
52.69
42.50
0.1562
17990.00
18115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1503.70
-17.09
59.0
51.0
109.0
256.0
10.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004807 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
T. forsythia ATCC 43037
32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0085906 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. agalactiae W73106655 or W70407881
16-32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0088385 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
P. gingivalis ATCC 33277
32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0180604 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
E. faecium W97542221
64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0210746 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9, 19 and 21 are dehydrated. Only one thioether ring between residues 9 and 14. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
anti-VRE, L-rhamnosus ATCC 11981
>64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
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