Peptide Database

Peptide NameDefensin alpha 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC441H720N126O139S8

DescriptionStandard

        MRITALLAAILLVALQVQAGPLQARGDEAAGQEQPGADDQDISISFAWDKSSALQVSGSTRGMVCSCRLVFCQRTELRVGNCVIGGISFTYCCTLVD
    

Molecular Weight10267.71 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0262

GRAVY Index0.34

Hydrophobic Moment 0.59

Boman Index0.13

Instability Index31.12

Aliphatic Index 99.59

Aromaticity 0.0515

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4259.28

LogP -48.68

H-bond Donors 154.0

H-bond Acceptors 145.0

Rotatable Bonds 341.0

Heavy Atoms 714.0

Ring Count 8.0

Amide Bonds 105.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0423728 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence