Peptide Database

Peptide NameHCC-1(9-74)

Function Ontology

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC344H520N92O104S6

DescriptionStandard

        GPYHPSECCFTYTTYKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN
    

Molecular Weight7800.75 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0287

GRAVY Index-0.92

Hydrophobic Moment 0.65

Boman Index-0.15

Instability Index26.91

Aliphatic Index 42.73

Aromaticity 0.1364

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14690.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3189.39

LogP -32.68

H-bond Donors 114.0

H-bond Acceptors 114.0

Rotatable Bonds 250.0

Heavy Atoms 546.0

Ring Count 17.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0433190 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCC chemokine

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-32; 9-48

Bio-Activity Profile

Function

Chemokine CCR agonist Chemotactic Anti-HIV

Targethuman CCR5

Activity0.04±0.01 nM

MethodKi

RECORD: Rec_0433191 VERIFIED: YES