Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2415H3745N583O679S18

DescriptionStandard

        MFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQICPLVADSIADINPHLKTLNVLAEVDQYGEFYNIGEHKEPPFSPIPFSFLSQDTDMIYIGVSAFTINSAGFVYNSAGALHSSGSPIRLNTKYTDDLFQIEKMYPGLMMKLLVETVKEPIVTFEPNNMTVQASKMFYNEFPFNQQEGSVSTHIYVTELKLAGNMTLNKIDISLAKSYVGPFQVTSLDNIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRLQVLKVSLCVCVCVYIYIYIYIYIYYYIYIYIYIYIYIYILYIYIYIYTHTYTGASQ
    

Molecular Weight52387.23 Da

Isoelectric Point (pI)7.58

Net Charge (pH 7.0)1.23

Net Charge (pH 7.4) 0.34

Charge Density (pH 7.0) 0.0026

GRAVY Index0.28

Hydrophobic Moment 0.68

Boman Index0.23

Instability Index23.23

Aliphatic Index 107.36

Aromaticity 0.1213

Extinction Coeff. Reduced 67160.00

Extinction Coeff. Oxidized 67535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417397 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria