Peptide Database

Peptide NameEsculentin-2CHa (11-37)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC125H218N34O35S2

DescriptionStandard

        KFASKGLGKDLAKLGVDLVACKISKQC
    

Molecular Weight2821.40 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.1384

GRAVY Index0.17

Hydrophobic Moment 0.58

Boman Index0.03

Instability Index13.72

Aliphatic Index 104.81

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1134.19

LogP -10.42

H-bond Donors 41.0

H-bond Acceptors 41.0

Rotatable Bonds 102.0

Heavy Atoms 196.0

Ring Count 1.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368891 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEsculentin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetAcinetobacter baumannii NM8

Activity200 μM

MethodMIC

FIRST PREV 1 2 3

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