Peptide Database

Peptide Namesynthetic peptide from alpha-gliadin

Function Ontology

Venom / Toxin ▸ General toxin ▸ Celiac toxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC61H105N17O20

DescriptionStandard

        EEIRNLALQTLP
    

Molecular Weight1396.59 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.16

Net Charge (pH 7.4) -1.33

Charge Density (pH 7.0) -0.0967

GRAVY Index-0.26

Hydrophobic Moment 0.38

Boman Index-0.03

Instability Index105.88

Aliphatic Index 138.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 617.54

LogP -5.04

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 46.0

Heavy Atoms 98.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350980 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin-derived

Tax ID4565;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Celiac toxic

Targetgliadin-reactive enterocyte / calreticulin cross-reactivity assays

PaperKrupickova S., Tuckova L., Flegelove Z., Michalak M., Walters J. R. F., Whelan A., Harries J., Vencovsky J., Tlaskalova-Hogenova H.. Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised antigliadin antibodies of patients with coeliac disease. Gut, 1999, 44, 168-173. PMID9895374 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9895374/

RECORD: Rec_0427042 VERIFIED: YES