Peptide Database

Peptide NameHuman beta defensin 3

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC171H295N51O51S4

DescriptionStandard

        GIISLLQKQFCSLRSGRCALLTCLPKEEQIGRCSLSG
    

Molecular Weight4009.74 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.46

Charge Density (pH 7.0) 0.0736

GRAVY Index0.22

Hydrophobic Moment 0.44

Boman Index0.03

Instability Index62.11

Aliphatic Index 108.11

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1665.12

LogP -18.76

H-bond Donors 63.0

H-bond Acceptors 58.0

Rotatable Bonds 139.0

Heavy Atoms 277.0

Ring Count 2.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066201 VERIFIED: YES

Provenance & Taxonomy

OrganismAcinonyx jubatus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)