Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC796H1202N178O242S8

DescriptionStandard

        QGIVYPAGNYTGSPCVAVPFTIPDQSDSMLYLAFPEYFFQTYSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEITKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTNQSLFTTNIAANTSISLNIFDQKLMASLCLNR
    

Molecular Weight17393.63 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.25

Net Charge (pH 7.4) -10.54

Charge Density (pH 7.0) -0.0653

GRAVY Index0.30

Hydrophobic Moment 0.56

Boman Index0.26

Instability Index48.78

Aliphatic Index 89.49

Aromaticity 0.1401

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6652.96

LogP -60.18

H-bond Donors 227.0

H-bond Acceptors 240.0

Rotatable Bonds 548.0

Heavy Atoms 1224.0

Ring Count 32.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126126 VERIFIED: NO

Provenance & Taxonomy

OrganismCrotophaga sulcirostris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria