Peptide Database

Peptide NameInsulin-like 3 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC114H181N35O36S4

DescriptionStandard

        AAATNPAHYCCLSGCSRQDLLTLCPH
    

Molecular Weight2746.13 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0027

GRAVY Index0.12

Hydrophobic Moment 0.27

Boman Index0.10

Instability Index60.81

Aliphatic Index 75.38

Aromaticity 0.0385

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1117.13

LogP -14.35

H-bond Donors 42.0

H-bond Acceptors 42.0

Rotatable Bonds 82.0

Heavy Atoms 189.0

Ring Count 5.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211014 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyInsulin-like

Tax ID9615

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-15

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour