Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC512H850N150O153S7

DescriptionStandard

        MLPDRSSTPSGSIKLLFLALAVLVVLAQTSPDGWLKKCYYGLGRCRKSCKEEEKKKEKCGKTLSCCLLSKNAKLSDFSPKPVTGEKWREREEREERGREGGGNKK
    

Molecular Weight11779.60 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)9.46

Net Charge (pH 7.4) 9.11

Charge Density (pH 7.0) 0.0901

GRAVY Index-0.81

Hydrophobic Moment 0.59

Boman Index-0.24

Instability Index46.00

Aliphatic Index 66.86

Aromaticity 0.0571

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4964.02

LogP -52.26

H-bond Donors 182.0

H-bond Acceptors 170.0

Rotatable Bonds 413.0

Heavy Atoms 822.0

Ring Count 13.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074873 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence