Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2328H3616N584O677S21

DescriptionStandard

        MLLTVTVLLMLIPSTCGKNPAVQVTLTDKGLQYGKHAGTDWFQDHLGNVTFPDISGGIKIKIFGTIDYALTGIKIIKCDLPEPSVDFYPDATGFKTSMSGLSIALNGEWRTHYGIIHDGGTFDMAVFDVSVLSVVELGKDDDGHLSISSVSCEAKVGDVNIVFQGGGSWIFQPFVHHFTGRIGREIQSRICPNVEQIIVTLEHHLQAMNVSFDVDQALSLDLSLTDLPVIDASKLNLGFKGEFYSIKSHTDPPFEAQPFTIPEQQGYMLAMGLSEYTLNSASYGYYSSGGFQAFINDSMIPPGCPVHLNTSLMGPFIPQLPKMFPGLLMYLQVYAIKAPMLSFHSDAIKLGVQANVKAFAIQPNGTETPLFKLGVDSQFNSKVWIDGQKVKGSVSMNNFTLTLVGSEVGEFETDPLERLAKLGVNLALTKVNVKMGKGFDLPRMKHSQLVNSVLKMQEGFIALFSDAEVL
    

Molecular Weight51290.48 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-12.37

Net Charge (pH 7.4) -13.43

Charge Density (pH 7.0) -0.0263

GRAVY Index0.11

Hydrophobic Moment 0.72

Boman Index0.19

Instability Index27.89

Aliphatic Index 94.32

Aromaticity 0.0957

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148391 VERIFIED: NO

Provenance & Taxonomy

OrganismEcheneis naucrates [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria