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MYP_029754
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Basic Information
Gageotetrin C
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Standard
4 amino acids
C23H42N4O7
Standard
Sequence
ELLL
Physicochemical Analysis
486.60 Da
4.05
-1.16
-1.33
-0.2908
1.98
0.35
0.61
7.50
292.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
187.92
0.86
6.0
6.0
16.0
34.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007336 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Botrytis cinerea
0.01 μM
MIC
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0040878 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human gastric cancer NUGC-3
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0045379 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MDA-MB-231
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0065759 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
E is a methoxy-Glu (esterized). The N-terminal C14 fatty acid is a 3-hydroxy-11-methyltridecanoic acid (HTDA). Variant: In the case of Gageotetrin C, the N-terminal C14 fatty acid is a 3-hydroxy-8,10-dimethyldodecanoic acid (HDDA)
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa
0.02-0.04 μM
MIC
PaperGageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.
RECORD: Rec_0069361 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human prostate adenocarcinoma PC-3
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
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