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MYP_029736
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Basic Information
P4 (Derived from PRW4)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C95H173N37O18
Standard
Sequence
RFRRLRPKTRPRLKKI
Physicochemical Analysis
2121.63 Da
12.00
8.76
8.55
0.5473
-1.73
0.38
-0.93
65.96
73.12
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
951.93
-7.59
37.0
27.0
74.0
150.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164298 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HaCaT cells in the range of 0/25-256 μM
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
RECORD: Rec_0170150 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis 12228
128 μM
MIC
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
RECORD: Rec_0171386 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium 7731
32 μM
MIC
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
RECORD: Rec_0197159 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 29212
128 μM
MIC
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
RECORD: Rec_0230588 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
hRBC
256 μM
MHC
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
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