Peptide Database

Peptide NameSLAY-screened peptide P1571

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC50H83N17O12

DescriptionStandard

        HVSRYRALL
    

Molecular Weight1114.30 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.2051

GRAVY Index-0.08

Hydrophobic Moment 0.27

Boman Index-0.17

Instability Index3.12

Aliphatic Index 130.00

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 489.06

LogP -3.52

H-bond Donors 19.0

H-bond Acceptors 15.0

Rotatable Bonds 35.0

Heavy Atoms 79.0

Ring Count 2.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344908 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/