Peptide Database

Peptide NamePaDBS1R6F10

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC60H109N17O11

DescriptionStandard

        KKLRLKIAFK
    

Molecular Weight1244.61 Da

Isoelectric Point (pI)11.33

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.4756

GRAVY Index-0.34

Hydrophobic Moment 0.02

Boman Index-0.32

Instability Index-12.24

Aliphatic Index 127.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 491.20

LogP -1.06

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 47.0

Heavy Atoms 88.0

Ring Count 1.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426986 VERIFIED: YES

Provenance & Taxonomy

OrganismPyrobaculum aerophilum [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae KpC+ 001825971

Activity32 μM

MethodMIC

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