Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC371H586N110O110S10

DescriptionStandard

        MEKKSLAGLCFLFLVLFVAQEIVVQTEARTCENLADTYRGPCFTTASCDDHCKNKEHLVRGRCRDDFRCWCTRNC
    

Molecular Weight8667.94 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.60

Net Charge (pH 7.4) 0.13

Charge Density (pH 7.0) 0.0080

GRAVY Index-0.23

Hydrophobic Moment 0.64

Boman Index-0.11

Instability Index24.61

Aliphatic Index 67.60

Aromaticity 0.0933

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3588.98

LogP -37.16

H-bond Donors 136.0

H-bond Acceptors 123.0

Rotatable Bonds 288.0

Heavy Atoms 601.0

Ring Count 11.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215018 VERIFIED: NO

Provenance & Taxonomy

OrganismSesbania javanica [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal

RECORD: Rec_0256757 VERIFIED: NO