Peptide Database

Peptide NameHelicostatin-9

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Invertebrate inhibitory neuropeptide

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Invertebrate inhibitory neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC61H91N19O17S

DescriptionStandard

        ERDMHRFSFGL
    

Molecular Weight1394.56 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.30

Charge Density (pH 7.0) -0.0068

GRAVY Index-0.83

Hydrophobic Moment 0.52

Boman Index-0.25

Instability Index61.16

Aliphatic Index 35.45

Aromaticity 0.1818

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 601.63

LogP -5.01

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 46.0

Heavy Atoms 98.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279374 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0326629 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicoverpa armigera [Animal]

FamilyHelicostatin

Tax ID29058

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

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