Peptide Database

Peptide NameRugosin-RN antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC369H604N94O119S5

DescriptionStandard

        MFTMKKSLLLLFFLGTISLSLCEEERGADEDDGEEMTEEEVKRSFLSKFKDIALDVAKNAGKGVLTTLARKIDGSC
    

Molecular Weight8421.63 Da

Isoelectric Point (pI)4.76

Net Charge (pH 7.0)-4.50

Net Charge (pH 7.4) -4.77

Charge Density (pH 7.0) -0.0592

GRAVY Index-0.13

Hydrophobic Moment 0.65

Boman Index-0.00

Instability Index39.20

Aliphatic Index 89.87

Aromaticity 0.0658

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3464.80

LogP -32.22

H-bond Donors 123.0

H-bond Acceptors 120.0

Rotatable Bonds 299.0

Heavy Atoms 587.0

Ring Count 5.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019352 VERIFIED: NO

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0044772 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal