Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length273 amino acids

Chemical FormulaC1354H2153N329O396S16

DescriptionStandard

        FLVSYDVNEVLTVELPLTSPPVISGDDVNLGLKGEFYSIETHQEPPFVAQPFVLPKEPNYMMSVGLSEFMLNSASFGYFSAGNLQVLVNDSMIPPKSPVHLNTTSMGMFIPQLPKLYPDMLMNLQVYATEAPMLSLQMDVVDVGAQLGAKAFAIEPNGTQVPLFTLSVETRLSGKMWIVDEKLKANAMLDNITLTLASSEVGTFKMDALENVVKMGINLMGLPKLNALLGDGIFLPQMKQAQLVNPVLKLEKGFLVVSSDTKIVQTNRNFNTL
    

Molecular Weight29889.58 Da

Isoelectric Point (pI)4.72

Net Charge (pH 7.0)-9.03

Net Charge (pH 7.4) -9.40

Charge Density (pH 7.0) -0.0331

GRAVY Index0.21

Hydrophobic Moment 0.57

Boman Index0.20

Instability Index38.62

Aliphatic Index 102.75

Aromaticity 0.0769

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400282 VERIFIED: NO

Provenance & Taxonomy

OrganismNothobranchius rachovii [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria