Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length234 amino acids

Chemical FormulaC1126H1735N297O310S9

DescriptionStandard

        ARLLSSVGAGGRRGSVTTPTLHPLLSFQGECFSLAQHTPVPFTPPALAVPPEHNRMVYFGVSSYFFNTASFAYHTAGALIFDITDAMVRRRGVGSVLDEMYPNMPMKFRLSAPSAPFLNIGTNGVSLQPVVDIQAYAIYPNGNLAPLFLLGLVSWGPWAGGAKEGPGVGSGRLLCTAPCSLSLLVPTQLCVFSFPERLGKGFPLPLPAQVQLSDPIVQFHEVSGGSGAGPATRP
    

Molecular Weight24681.21 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.68

Charge Density (pH 7.0) 0.0137

GRAVY Index0.23

Hydrophobic Moment 0.60

Boman Index0.22

Instability Index41.26

Aliphatic Index 87.52

Aromaticity 0.0983

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337366 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos platyrhynchos [Animal]

FamilyBPI

Tax ID8840

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence