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MYP_029533
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition
Standard
6 amino acids
C38H50N10O7S
Standard
Sequence
HCKFWA
Physicochemical Analysis
790.93 Da
8.23
0.84
0.57
0.1394
-0.15
0.31
0.17
-16.72
16.67
0.3333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
279.31
-0.17
11.0
10.0
22.0
56.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 8524782 PMID8524782 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8524782/
RECORD: Rec_0133731 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Integrase inhibition
E.coli
210 μM
IC50
PaperViral integrase inhibiting peptides PatentUS5578573
RECORD: Rec_0207638 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Integrase inhibition
Qualitative inhibition
PaperIdentification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library. PMID8524782 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8524782/
RECORD: Rec_0398352 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibition of integrase-mediated 3'-processing and integration
210 μM
IC50
PaperPubMed PMID: 8524782 PMID8524782 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8524782/
RECORD: Rec_0399453 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
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