Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC401H645N111O121S13

DescriptionStandard

        MKTLSVAVAVAVVLAFICLPESSAVPVTEVQELEEPMSNDNLAAAHEDMSVESWKMPYNNRQKRGIKCRFCCGCCTPGVCGVCCRF
    

Molecular Weight9373.93 Da

Isoelectric Point (pI)5.72

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0173

GRAVY Index0.22

Hydrophobic Moment 0.47

Boman Index0.09

Instability Index63.46

Aliphatic Index 78.14

Aromaticity 0.0581

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3685.56

LogP -38.19

H-bond Donors 134.0

H-bond Acceptors 134.0

Rotatable Bonds 304.0

Heavy Atoms 646.0

Ring Count 12.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001241 VERIFIED: NO

Provenance & Taxonomy

OrganismMicropterus dolomieu [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0237773 VERIFIED: YES