Peptide Database

Peptide NameSLAY-screened peptide P4361

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC57H97N11O13S2

DescriptionStandard

        CVYAVICIIVI
    

Molecular Weight1208.58 Da

Isoelectric Point (pI)5.51

Net Charge (pH 7.0)-0.26

Net Charge (pH 7.4) -0.49

Charge Density (pH 7.0) -0.0237

GRAVY Index3.28

Hydrophobic Moment 0.13

Boman Index0.93

Instability Index9.19

Aliphatic Index 230.00

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 374.55

LogP 1.23

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 36.0

Heavy Atoms 83.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041548 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/