Peptide Database

Peptide NameToxin Ctri18

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC200H321N65O64S7

DescriptionStandard

        GTNHTNEPCTPNKTSHCRAYCTKEFGIRSSKCMNEKCVCYGRK
    

Molecular Weight4884.54 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.88

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.1134

GRAVY Index-1.08

Hydrophobic Moment 0.42

Boman Index-0.31

Instability Index39.02

Aliphatic Index 18.14

Aromaticity 0.0698

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2127.66

LogP -29.80

H-bond Donors 81.0

H-bond Acceptors 78.0

Rotatable Bonds 162.0

Heavy Atoms 336.0

Ring Count 7.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402402 VERIFIED: YES

Provenance & Taxonomy

OrganismChaerilus tricostatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Kv1.3 channel blocker

TargetKv1.3 potassium channel

Methodelectrophysiological Kv1.3 channel inhibition assay

RECORD: Rec_0433168 VERIFIED: YES