Peptide Database

Peptide NameColicin pyocin immunity family protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length639 amino acids

Chemical FormulaC3041H4887N885O915S11

DescriptionStandard

        MGEGHSNTTGHGARGPTGGVKGGPAGPGGPGSSRGQGWGTSQTSYGAIHHYSPSQFGHGSQRGGRRGGDRSSKATPANLAQNPELQTYMVVGGMPAVITLIDGNWGVTLSRLPAVAAFIEGHLARVGSWVMRTSPVGVAVMGMIPSRIASDPPIGQFFTTSTLPANRVTDTPKETLKAVADAAVNIRIGDVTEEGVQKAVLIKAPIAIQRVPVIKAVTTTRPDVVTAAIPGITPIHISVVDTMPINIPAPIQPAARPVVTPIENAAPKEFSLPVGRHSRDAIIVFPDSTGIEPLYLSVIRITNADELMQEARNTYEIARNEREAAERAMTQSFSSALDELKLKKTLKDKQVTEIAAHIILLESHIPLLKQEEANIWQQYNAFGGRDNKWAFKYRYERRDLRALALVKQEEVNAINYRLVELRAKYETLLVLQQSVNAELGIARIAEQQRIENTRLAAEAAERQQRVENAPRAIEAAFAAERQRIEERWLAVEAEAAIRNNTFSLSVYPPGSVHSPSFAVGGAGAITLSPQVVNHLGASLRRVSERFHGIDTSSLADPMAVIIGAGFYPDNDRESTNKPPLAGSFSLSDIGLVPSTPLPRQGEIELPVRILMEEKNDWTSIYAVKTHAANVAAKVKVGQA
    

Molecular Weight68838.43 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.83

Net Charge (pH 7.4) 3.76

Charge Density (pH 7.0) 0.0076

GRAVY Index-0.21

Hydrophobic Moment 0.76

Boman Index0.03

Instability Index48.11

Aliphatic Index 89.67

Aromaticity 0.0548

Extinction Coeff. Reduced 57870.00

Extinction Coeff. Oxidized 57870.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003648 VERIFIED: NO

Provenance & Taxonomy

OrganismYersinia enterocolitica [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence