Peptide Database

Peptide NameT645

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC187H294N52O68

DescriptionStandard

        DREINNYTSLIHSLIEESQNQQEKNEQELLELDKWA
    

Molecular Weight4358.64 Da

Isoelectric Point (pI)4.29

Net Charge (pH 7.0)-6.13

Net Charge (pH 7.4) -6.40

Charge Density (pH 7.0) -0.1704

GRAVY Index-1.28

Hydrophobic Moment 0.58

Boman Index-0.25

Instability Index58.78

Aliphatic Index 89.44

Aromaticity 0.0556

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2021.80

LogP -21.16

H-bond Donors 66.0

H-bond Acceptors 63.0

Rotatable Bonds 154.0

Heavy Atoms 307.0

Ring Count 4.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124707 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetCEM

Activity0.085 μg/mL

MethodIC50

RECORD: Rec_0187142 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 94.4%, E 0.0%, T 0.0%, C 5.6% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial