Peptide Database

Peptide NameAtezolizumab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immuno-oncology

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2191H3370N580O665S15

DescriptionStandard

        EVQLVESGGGLVQPGGSLRLSCAASGFTFSDSWIHWVRQAPGKGLEWVAWISPYGGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARRHWPGGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYASTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight48956.66 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 3.71

Charge Density (pH 7.0) 0.0105

GRAVY Index-0.37

Hydrophobic Moment 0.57

Boman Index0.03

Instability Index46.38

Aliphatic Index 69.53

Aromaticity 0.0982

Extinction Coeff. Reduced 88810.00

Extinction Coeff. Oxidized 89435.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073078 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyMonoclonal antibody

Tax ID10090

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation

Bio-Activity Profile

Function

Anticancer Immunomodulatory Immuno-oncology

Half-LifeTerminal half-life was 27 days