Peptide Database

Peptide NameCorazonin precursor-related peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC185H314N50O69S

DescriptionStandard

        SPLSSSSSSPSSSAAMEPLTANQLLASALSSGGLNSLKPSEKALL
    

Molecular Weight4374.83 Da

Isoelectric Point (pI)5.86

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0119

GRAVY Index0.04

Hydrophobic Moment 0.42

Boman Index0.13

Instability Index78.17

Aliphatic Index 91.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1888.15

LogP -30.43

H-bond Donors 65.0

H-bond Acceptors 70.0

Rotatable Bonds 143.0

Heavy Atoms 305.0

Ring Count 4.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114246 VERIFIED: NO

Provenance & Taxonomy

OrganismAnopheles gambiae [Animal]

FamilyCorazonin precursor-related peptide

Tax ID7165

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0132267 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0307756 VERIFIED: NO

Provenance & Taxonomy

OrganismAnopheles gambiae [Animal]

FamilyCorazonin

Tax ID7165

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone