Peptide Database

Peptide NameMP-VB2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC66H120N18O16S

DescriptionStandard

        INMKAVAAVAKKPL
    

Molecular Weight1453.83 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1969

GRAVY Index0.64

Hydrophobic Moment 0.46

Boman Index0.18

Instability Index3.90

Aliphatic Index 125.71

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 553.98

LogP -3.29

H-bond Donors 18.0

H-bond Acceptors 20.0

Rotatable Bonds 49.0

Heavy Atoms 101.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0135886 VERIFIED: NO

Provenance & Taxonomy

OrganismVespa bicolor [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Hormone

RECORD: Rec_0433158 VERIFIED: YES

Provenance & Taxonomy

OrganismVespa bicolor [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Hemolysis tested Non-hemolytic

Targethuman red blood cells

Activity0 %

MethodHemolysis assay (320 μg/mL peptide)

RECORD: Rec_0433159 VERIFIED: YES

Provenance & Taxonomy

OrganismVespa bicolor [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Hemolysis tested Non-hemolytic

Targetrat red blood cells

Activity0 %

MethodHemolysis assay (320 μg/mL peptide)

RECORD: Rec_0433160 VERIFIED: YES

Provenance & Taxonomy

OrganismVespa bicolor [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Mast-cell degranulation Low degranulation activity

TargetRBL-2H3 cells

Activity>200 μM

MethodMast-cell degranulation EC50 (β-hexosaminidase release)

RECORD: Rec_0433161 VERIFIED: YES

Provenance & Taxonomy

OrganismVespa bicolor [Animal]

FamilyMastoparan

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsC-terminal amidation

Bio-Activity Profile

Function

Mast-cell degranulation Low degranulation activity

TargetP815 cells

MethodMast-cell degranulation assay at 80 μg/mL (β-hexosaminidase release; low activity)