Peptide Database

Peptide NamePyocin-S2 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length552 amino acids

Chemical FormulaC2643H4134N758O810S17

DescriptionStandard

        MAKGYILHMYDPTTCGGKVLEGAPNRRTNGTPVARMGDKVTCGKDGNTYRIVGGMSWITTEGRLVAGSLDSYSSCPCNAKIIPRIMVQTYETRRGIGAKTSNTATSAVTQGSPSSSSPAIITPLPVAVYAKSCLRGEGCTDAGTEQELFDNFGHAGYYRATPQTEQVKEEPVQHAQAAKKHKPAEPTPPPEDKRSWYKRLFSSPDTTKAEAAAGMAIARAATTTGITTGATTEAGCAALQQIGGTLSTAGRWIAPSPPTVLLFGMFYSPKLNSGEQDYIDKMRLEQAAQNKEDVPTRVRFRWEADQNGMIRPKGFHVSARGGQDKVPVRMLQKNTTTGNYEFWEDGASKPTIVWTPDDPGYVSPSNTGNRDNVYVPPSVLVYPESEINSPWSTVTPAPGERSFRDYILVHPAGTFDPIYVYLRNLPGQVTGKGQKVSGAWLADANQGTGSPIPSQIADKLRGRTFSNFDSFRQAFWLEVSKDPELSQQFRQHNLGNIRNGKAPAPRISEQVGGKIKYDIHHIKPIVEGGEVYDVDNLGVVTPKRHIEIHRGG
    

Molecular Weight60032.80 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)9.45

Net Charge (pH 7.4) 8.43

Charge Density (pH 7.0) 0.0171

GRAVY Index-0.55

Hydrophobic Moment 0.64

Boman Index-0.04

Instability Index49.69

Aliphatic Index 64.87

Aromaticity 0.0797

Extinction Coeff. Reduced 79300.00

Extinction Coeff. Oxidized 79675.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229177 VERIFIED: NO

Provenance & Taxonomy

OrganismKluyvera ascorbata [Bacterium]

FamilyColicin/Bacteriocin

Tax ID1006000

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence