Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC931H1400N210O280S9

DescriptionStandard

        VDDLAEVDYSFNNLPAVFQSFIDLDLKGIVYPAGNYAGPPYMAVPFAIPDRSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCNYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVVSLEQDSFTVEIQGSMEVFAVLPDSTNQSLFTMNIVANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20302.90 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.26

Net Charge (pH 7.4) -14.55

Charge Density (pH 7.0) -0.0779

GRAVY Index0.32

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index49.35

Aliphatic Index 92.73

Aromaticity 0.1421

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7758.21

LogP -79.76

H-bond Donors 261.0

H-bond Acceptors 275.0

Rotatable Bonds 643.0

Heavy Atoms 1430.0

Ring Count 37.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242702 VERIFIED: NO

Provenance & Taxonomy

OrganismTrogon melanurus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria