Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length231 amino acids

Chemical FormulaC1124H1723N303O309S8

DescriptionStandard

        GRGWGPPPGPVLTPPAFPSQDSGVVQLHVADLATDPNVHLSVLSTQGEFFGVGRRWQSPFSPKPVGLPEAHEPMVLLALTEFVANSAAFVYFTAGALRRNISGEAVRGGLQTKSLGSFSPQELFPDLPMELQLSARRQPLLSCHPDALHGTLYGSAEAFVVLPNATRAPVFLLDIVSAWPRGAGVLLGSYWGLTGSYWVLLGSYWVLLGPCGCCRHCPSVPNVPSRCRTPT
    

Molecular Weight24681.07 Da

Isoelectric Point (pI)7.82

Net Charge (pH 7.0)1.25

Net Charge (pH 7.4) 0.62

Charge Density (pH 7.0) 0.0054

GRAVY Index0.12

Hydrophobic Moment 0.59

Boman Index0.18

Instability Index52.15

Aliphatic Index 88.61

Aromaticity 0.0952

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133110 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos (Mallard) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria