Peptide Database

Peptide NameMPHW

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC27H35N7O5S

DescriptionStandard

        MPHW
    

Molecular Weight569.68 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-0.41

Net Charge (pH 7.4) -0.68

Charge Density (pH 7.0) -0.1031

GRAVY Index-0.95

Hydrophobic Moment 0.37

Boman Index0.29

Instability Index110.15

Aliphatic Index 0.00

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 186.30

LogP 0.80

H-bond Donors 6.0

H-bond Acceptors 7.0

Rotatable Bonds 13.0

Heavy Atoms 40.0

Ring Count 4.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268750 VERIFIED: YES

Provenance & Taxonomy

OrganismMomordica charantia [Plant]

FamilyFood-derived bioactive peptide

Tax ID3673

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory ACE inhibitory Antidiabetic Antihypertensive

TargetDPP-IV; ACE

Activity128.0 ± 1.3 μM

MethodIC50