Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC751H1171N223O223S6

DescriptionStandard

        MSRVQFKQRESTDAIFVHCSATKPSQNVGVREIRQWHKERGWLDVGYHFIIKRDGTVEAGRDEMAVGSHAKDYNHNSIGVCLVGGIDDKGKFDANFTPDQMQSLRSLLVTLLAKYEGAVLRAHHDVAPKACPSFDLKRWWETNELVTSDRG
    

Molecular Weight17084.08 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.45

Charge Density (pH 7.0) 0.0073

GRAVY Index-0.54

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index40.19

Aliphatic Index 73.58

Aromaticity 0.0861

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7222.77

LogP -74.43

H-bond Donors 256.0

H-bond Acceptors 237.0

Rotatable Bonds 571.0

Heavy Atoms 1203.0

Ring Count 28.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232950 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus phage EFA-2 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic