MYP_029310
Potassium channel toxin alpha-KTx 2.16
Membrane / Ion-channel modulation
▸
Ion channel modulation
Venom / Toxin
▸
General toxin
▸
Toxin
Standard
39 amino acids
C187H312N52O52S7
Standard
TIINVKCTSPKQCLKPCKDLYGPHAGEKCMNGKCKCYKI
4345.25 Da
9.19
5.42
5.07
0.1390
-0.48
0.57
-0.10
27.69
60.00
0.0513
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1684.61
-16.52
62.0
66.0
147.0
298.0
6.0
41.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0082739
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Potassium channel blocker
potassium channel KCa3.1/KCNN4
0.056 μM
IC50
RECORD: Rec_0261621
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Potassium channel blocker
Kv1.2/KCNA2
0.0007 μM
IC50
RECORD: Rec_0390416
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Potassium channel blocker
Kv1.3/KCNA3
0.0262 μM
IC50