Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length169 amino acids

Chemical FormulaC812H1309N233O241S17

DescriptionStandard

        MRAGGVLTSLRGRAELSWRQMRASRTAATTATLKVFISGGLNCSNWFRALTLVQEKSEELTRVTCTRVKARNQLEQFSPPEMKTFSVAVVAAVLLALICLQESSALPLSELEDVEVPVMDDNGAAVYEEMPVDSWKMPYTNIYKRRPQRCRFCCNCCPGIQGCGPCCGF
    

Molecular Weight18736.60 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)3.42

Net Charge (pH 7.4) 3.01

Charge Density (pH 7.0) 0.0202

GRAVY Index-0.06

Hydrophobic Moment 0.54

Boman Index-0.00

Instability Index52.75

Aliphatic Index 79.05

Aromaticity 0.0710

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7626.05

LogP -80.72

H-bond Donors 278.0

H-bond Acceptors 262.0

Rotatable Bonds 615.0

Heavy Atoms 1303.0

Ring Count 24.0

Amide Bonds 181.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0047153 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu rubripes [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal