Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1193 amino acids

Chemical FormulaC5833H9091N1663O1786S34

DescriptionStandard

        MDNRSAFFDGQTRYFLEINGSAVKPDVLRFRGREALSEPFRWDIGFTSRNANIPPEEVLMKYASLRMRNGKNVHGIVTRLEWLSTSKDQSHYRLTLSSRLALLEYTRQCAVFQNQSVPEVVEQVLRKHGLEGADFEFRLERAYPSREIITQWQETDLQFIQRILSEVGIYWRTEMDDVCGLDTYIFADSQLHYKFDVQLPYSEPSELLDGAAESVWDVRTWHNVATGTVTTRDYNYRTAAMPMNATVSVRNDAVTTGEHYRYAAPYREAGDDASPEPETESGAFYARLHHERELNRSARIHLFSNAAHLSPGQVLEPQGDVITDLKEGIVLTLVTYRGARDTRLHVSARGMPYTERYCFRPAEIPRPVIPGTLPARIESRGKNDIYAHLDGQGRYRVKMDFDREETEPGYGYLWLRMAKPCAGETLGWHTPLIDGTEVAIAYSNGDIDLPYIAYALHDAEHPDPVNRDNHTRNILRTSANSKLRMEDWRGGEHIKLATEYGKTQLNSGHLVDSQGQLRGKGTELRTDEWGTLRAGKGLFVAADAQAKAQGEVLDMDAALKEIDRLTQQLQQLENAAERAQALKADIDSQRQMFEQRLKPLNEAVLFSAPEGIALTSGEDVQLAAGQNLAVNAGGDISTGTMGNLTALAGEKLGLFARTGQLSVKSGEGPVEVQAQNGSMRLFAEKKLALSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTASYLRKVKRTMAASASSEAAQTVSLPTPVTMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVEHFGQMTIFARPVEDDCCGYGRQHEHTDDEVIQHAQSARKRKPDVGGAKAPAPAGATAAPLALGAVTGVMTQVWGEWSLTGVLGAARGIPYIGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMQVYGVHTGEGTPYEGVRTANMVWNSQNNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSGIKLPDQATILVTPIPDGKDEYTTSPFPVPEERDFNDYILVFPAGSGIKPIYVYLKTARDEPGVATGKGKILSGSEKWLEAASSGLGAPVPAQVASKLRGKSFRNFDHFREEFWLAVSECPELMKDFKPSNQILIRMGLAPYPVPSEQVGGRTTFELHHPEEIQHGGEVFNMDNINVTTPRLHIGIHKNANR
    

Molecular Weight132179.86 Da

Isoelectric Point (pI)5.79

Net Charge (pH 7.0)-21.65

Net Charge (pH 7.4) -23.90

Charge Density (pH 7.0) -0.0181

GRAVY Index-0.49

Hydrophobic Moment 0.78

Boman Index-0.04

Instability Index34.56

Aliphatic Index 74.46

Aromaticity 0.0838

Extinction Coeff. Reduced 167080.00

Extinction Coeff. Oxidized 167580.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104431 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyVgrG protein

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli