Peptide Database

Peptide NameEsculentin-2S protein

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC375H627N97O114S6

DescriptionStandard

        MFTLKKSLLVLFFLGTISLSLCEQERAADDEDNGEVEEVKRGLFTLIKGAVKMIGKTVAKEAGKTGLELMACKVTNQC
    

Molecular Weight8510.96 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0066

GRAVY Index0.12

Hydrophobic Moment 0.65

Boman Index0.07

Instability Index16.48

Aliphatic Index 100.00

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3426.73

LogP -30.56

H-bond Donors 121.0

H-bond Acceptors 120.0

Rotatable Bonds 302.0

Heavy Atoms 592.0

Ring Count 4.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109426 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana schmackeri [Animal]

Tax ID110116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal