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MYP_029227
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Basic Information
RI16 (Derived from PMAP-36)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C97H183N39O18
Standard
Sequence
RFRRLRKKTRKRLKKI
Physicochemical Analysis
2183.74 Da
12.00
10.76
10.54
0.6722
-2.02
0.64
-1.13
66.97
73.12
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1021.55
-8.34
41.0
29.0
84.0
154.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0325049 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa LCCE
256 μM
MIC
PMID24021230;25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24021230/
RECORD: Rec_0327562 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa LCGE
256 μM
MIC
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0340121 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
256 μM
HC50
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0356529 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus 29213
128 μM
MIC
PaperDesign of imperfectly amphipathic alpha-helical antimicrobial peptides with enhanced cell selectivity.
RECORD: Rec_0359256 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis 12228
32 μM
MIC
PaperDesign of imperfectly amphipathic alpha-helical antimicrobial peptides with enhanced cell selectivity.
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