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MYP_029173
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Basic Information
Neuromedin-U-23
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
23 amino acids
C125H184N34O34
Standard
Sequence
FKAEYQSPSVGQSKGYFLFRPRN
Physicochemical Analysis
2707.01 Da
9.99
2.76
2.55
0.1200
-0.94
0.31
-0.16
68.10
33.91
0.2174
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1129.50
-11.28
39.0
37.0
86.0
193.0
7.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0433148 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Neuromedin U
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Immunomodulatory NMUR1 agonist ILC2 activation Type-2 cytokine induction
NMUR1; mouse ILC2 cells
ILC2 activation / cytokine production assay; in vivo NmU23 administration
PaperNeuronal regulation of type 2 innate lymphoid cells via neuromedin U PMID28869974
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