Peptide Database

Peptide NameMelanin-concentrating hormone

Function Ontology

Cardiovascular

Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier

Delivery / Targeting ▸ Drug delivery vehicle

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC105H162N30O26S4

DescriptionStandard

        DFDMLRCMLGRVYRPCWQV
    

Molecular Weight2388.85 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.51

Charge Density (pH 7.0) 0.0390

GRAVY Index-0.03

Hydrophobic Moment 0.69

Boman Index-0.07

Instability Index41.09

Aliphatic Index 71.58

Aromaticity 0.1579

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 917.74

LogP -5.05

H-bond Donors 35.0

H-bond Acceptors 31.0

Rotatable Bonds 75.0

Heavy Atoms 165.0

Ring Count 5.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0433147 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyMelanin-concentrating hormone

Structure & Mods

Configdisulfide-constrained peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-16

Bio-Activity Profile

Function

Feeding regulator Orexigenic Neuropeptide Hormone

TargetRattus norvegicus

Methodintracerebroventricular administration / food-intake assay

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