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MYP_029160
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Basic Information
Melanin-concentrating hormone
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
19 amino acids
C105H162N30O26S4
Standard
Sequence
DFDMLRCMLGRVYRPCWQV
Physicochemical Analysis
2388.85 Da
8.06
0.74
0.51
0.0390
-0.03
0.69
-0.07
41.09
71.58
0.1579
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
917.74
-5.05
35.0
31.0
75.0
165.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0134143 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Melanin-concentrating hormone
9606
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-16
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Feeding regulator
a broad array of neuron
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Melanin-concentrating hormone (Homo sapiens): PMID 10037747 PMID10037747 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10037747/
RECORD: Rec_0155974 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Mus musculus [Animal]; Pig [other]; Porcine [other]; Rattus norvegicus [Animal]
9606; 10090; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
7-16
Bio-Activity Profile
-
RECORD: Rec_0160113 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Melanin-concentrating hormone
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator
PMID2759038 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2759038/
RECORD: Rec_0183921 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0234254 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Melanin-concentrating hormone
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator
PMID2759038 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2759038/
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