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MYP_029152
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Basic Information
Anal 6 (antimicrobial peptide HP (2-20)analogue)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
19 amino acids
C116H187N29O24
Standard
Sequence
AKKVFKRLEKLFSKIFNFK
Physicochemical Analysis
2371.91 Da
10.68
5.79
5.59
0.3049
-0.34
0.85
-0.17
-10.51
82.11
0.2105
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
905.76
-3.32
32.0
30.0
86.0
169.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
3.13 μg/mL
MIC
PaperInteractions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-114. doi: 10.1042/BJ20051574. PMID: 16255716. PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0036408 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Aspergillus fumigatus
50-25 μg/mL
MIC
PaperInteractions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-114. doi: 10.1042/BJ20051574. PMID: 16255716. PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0041428 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
3.13 μM
MIC
PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0075230 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Listeria monocytogenes
0.78 μg/mL
MIC
PaperInteractions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-114. doi: 10.1042/BJ20051574. PMID: 16255716. PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
RECORD: Rec_0080652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus epidermidis
6.25 μg/mL
MIC
PaperInteractions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-114. doi: 10.1042/BJ20051574. PMID: 16255716. PMID16255716 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16255716/
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