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MYP_029139
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Basic Information
Calcitonin
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
32 amino acids
C148H229N39O47S3
Standard
Sequence
CGNLSTCMLGTYTQDLNKFHTFPQTSIGVGAP
Physicochemical Analysis
3402.83 Da
6.72
-0.17
-0.46
-0.0054
-0.04
0.47
0.18
37.23
60.94
0.0938
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1374.04
-17.39
48.0
51.0
106.0
237.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093438 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Calcitonin
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Hormone Calcium-regulatory peptide
PMID1278175 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1278175/
RECORD: Rec_0207345 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Calcitonin
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Amidation
1-7
3:N-linked (GlcNAc...) asparagine
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory ACE inhibitory Feeding regulator
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Calcitonin (Rattus norvegicus): PMID 1278175 PMID1278175 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1278175/
RECORD: Rec_0277356 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0394924 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Calcitonin
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Hormone