Peptide Database

Peptide Namedefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC460H738N134O133S8

DescriptionStandard

        MKVMVFLALALVLVGVVQAQPVADKSPKEVLEVHTLEEDLPENADVQEHSRQKRATCDLLSKWNWNHTACAAHCLARKYKGGYCNDKAVCVCRH
    

Molecular Weight10530.12 Da

Isoelectric Point (pI)7.64

Net Charge (pH 7.0)0.89

Net Charge (pH 7.4) 0.30

Charge Density (pH 7.0) 0.0095

GRAVY Index-0.18

Hydrophobic Moment 0.54

Boman Index-0.02

Instability Index40.01

Aliphatic Index 90.21

Aromaticity 0.0532

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4290.85

LogP -39.72

H-bond Donors 152.0

H-bond Acceptors 147.0

Rotatable Bonds 350.0

Heavy Atoms 735.0

Ring Count 15.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225769 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila bipectinata [Animal]

FamilyDefensin

Tax ID42026

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal