Peptide Database

Peptide NameApl_AvBD-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC203H311N63O49S7

DescriptionStandard

        PGLSSPRRDMFFCRKGSCHFGRCPFHLVKVGSCFGFRSCCK
    

Molecular Weight4642.49 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)7.07

Net Charge (pH 7.4) 6.82

Charge Density (pH 7.0) 0.1725

GRAVY Index-0.13

Hydrophobic Moment 0.61

Boman Index-0.08

Instability Index79.78

Aliphatic Index 33.17

Aromaticity 0.1463

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1779.12

LogP -19.35

H-bond Donors 72.0

H-bond Acceptors 65.0

Rotatable Bonds 149.0

Heavy Atoms 322.0

Ring Count 11.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0319586 VERIFIED: YES

Provenance & Taxonomy

OrganismCariama cristata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)