Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC408H647N117O105S4

DescriptionStandard

        MKARLHCVAVGLMLWMGSSRFGEGTANPGIVVQITRKGLEYAHQYAIAILKKELSTIKVPNLSGHFRIRWVGSVSYDFHR
    

Molecular Weight8999.48 Da

Isoelectric Point (pI)10.21

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.39

Charge Density (pH 7.0) 0.0855

GRAVY Index0.05

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index24.36

Aliphatic Index 96.25

Aromaticity 0.1000

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3556.76

LogP -29.18

H-bond Donors 129.0

H-bond Acceptors 120.0

Rotatable Bonds 298.0

Heavy Atoms 634.0

Ring Count 16.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102799 VERIFIED: NO

Provenance & Taxonomy

OrganismDipodomys ordii [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria