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MYP_028996
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Basic Information
A5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
14 amino acids
C84H164N30O15
Standard
Sequence
LILKRKRKRKRILI
Physicochemical Analysis
1834.39 Da
12.00
7.76
7.55
0.5540
-0.62
0.28
-0.63
123.88
167.14
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
793.30
-3.45
31.0
23.0
71.0
129.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171248 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Tumor cells: U-937
Qualitative functional evidence
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0312693 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Tumor cells: U-937
Qualitative functional evidence
PaperRational design of artificial beta-strand-forming antimicrobial peptides with biocompatible properties. Mol Pharm. 2014 Oct 6;11(10):3492-3502. doi: 10.1021/mp500271c. PMID: 25192319. PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0380289 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0388139 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
128 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
RECORD: Rec_0419648 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 12600
128 μM
MIC
PMID25192319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25192319/
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