Peptide Database

Peptide NameG4-12A gliadin (p62-p75; E65 and A73)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC77H109N17O22

DescriptionStandard

        PQPELPYPQPQAPY
    

Molecular Weight1624.79 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0743

GRAVY Index-1.47

Hydrophobic Moment 0.13

Boman Index-0.03

Instability Index126.81

Aliphatic Index 35.00

Aromaticity 0.1429

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 590.71

LogP -3.72

H-bond Donors 16.0

H-bond Acceptors 21.0

Rotatable Bonds 40.0

Heavy Atoms 116.0

Ring Count 8.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029480 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: G4; Reported substitutions/positions: E65; Reported substitutions/positions: A73; Reported substitution variant

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay